You both really do have a lot going on, that can be really taxing (to say the least) - and personally there is very little that I'm happy about at 8:15 a.m. :-) (unless it's Sunday, then I'm good). I'm wondering - for both of you - if you have people to talk to? I mean therapy would be great, but difficult if you're going on the road, but even just close friends who you can talk to individually. Working together through all of this is great, but you do both have individual needs as well. And with HRT, typically they'll do blood work first, so you'd have to wait a little anyway. And my own experience with it was that I did feel it, but it wasn't very disruptive. As I recall I just started noticing that I felt all emotions a little more than I had been (happy, sad, angry, etc., they were all just a little stronger). They also start you slow. I did accidentally double my dosage once - the pharmacy had changed the pills so that they were double what they had been and I kept taking the same number - once I realized (about a week) I went back and realized it had been having a pretty big impact - so the moral of the story is "stick with the correct dosage!" :-)