Dani,
I think I see your point. An example might be use of the "n-word" for blacks. I occasionally hear one black using it to another as if they have a common bond, like "Hey bro, mind if I ask a favor of you?" (Replace 'bro' with the n-word.) But, notice that even in this message I'm not spelling out the n-word. Why? Because I know how much weight and hurt that word carries.
"Tranny" has similar baggage. As does "she-male" and others. Oh sure, I can imagine that in the right setting, I might joke with Veronica that way if we were both dressed en femme. But for me I'd prefer not to hear it.
What about changing public perception? I think we have enough to contend with regarding acceptance and support for trans people. Trying to also "change the meaning" of what is used as a derogatory slur seems too much.
I recall the days in the 60s when my grandfather used the n-word when talking about blacks. And I remember when "black" and "gay" words emerged as friendly terms for blacks and homosexual men. I think we need to follow in their footsteps.
Last, I'd like to express my appreciation for your bringing this up for discussion here. That's a good thing to do. You go, Girl!
Emma